In some people, this change happens faster and more completely than usual, which increases the risk of very serious side effects. Get medical help right away if you notice any of the following:. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at Before taking this medication, tell your doctor or pharmacist if you are allergic to codeine, acetaminophen, or caffeine; or to other opioid pain medications such as morphine ; or if you have any other allergies.
This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of:. This drug may make you dizzy or drowsy. Alcohol or marijuana cannabis can make you more dizzy or drowsy.
Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana cannabis. Before having surgery or certain medical procedures such as a heart stress test or a procedure to restore a normal heart rhythm if you have an unusually fast heartbeat , tell your doctor or dentist that you use this medication and about all the products you use including prescription drugs, nonprescription drugs, and herbal products.
See also Warning section. It may harm an unborn baby. Discuss the risks and benefits with your doctor. This medication passes into breast milk and may have undesirable effects on a nursing infant, such as unusual sleepiness, difficulty feeding, trouble breathing, or unusual limpness. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Tell your doctor or pharmacist if you are taking other products such as other opioid pain or cough relievers such as morphine, hydrocodone , alcohol, marijuana cannabis , drugs for sleep or anxiety such as alprazolam, lorazepam, zolpidem , muscle relaxants such as carisoprodol, cyclobenzaprine , or antihistamines such as cetirizine, diphenhydramine.
Check the labels on all your medicines such as allergy or cough-and-cold products, pain relievers because they may also contain acetaminophen, caffeine, or ingredients that cause drowsiness. Ask your pharmacist about using those products safely. Other medications can affect the removal of this product from your body, which may affect how this product works. Examples include azole antifungals such as ketoconazole , bupropion, fluoxetine, macrolide antibiotics such as erythromycin , HIV medications such as ritonavir , paroxetine, quinidine, rifamycins such as rifabutin, rifampin , certain drugs used to treat seizures such as carbamazepine, phenytoin , among others.
Avoid drinking large amounts of beverages containing caffeine coffee, tea, colas and eating large amounts of chocolate. Codeine is metabolized by the body into morphine. At higher doses, morphine and other opioids can cause feelings of elation, analgesia, and euphoria as well as dangerous side effects, including stopping of the heart and brain damage.
Common side effects of codeine include:. Common side effects of acetaminophen include:. In rare cases, acetaminophen can cause a severe skin reaction that can be fatal. Call your doctor immediately if you experience any of the following side effects:. The half-life of a medication is the time it takes for the drug to decrease to half of its original concentration, or put another way, the time it takes for half of a dose to be eliminated from the body.
The half-lives of the components of Tylenol 3 are slightly different:. Urine screenings, which are the most commonly used drug tests because they are relatively easy and cost-effective to administer, can detect the codeine in Tylenol 3 in your system for up to three days after use. Blood tests, which are used less frequently because they are more invasive and costly than urine tests, have a hour window for detecting the codeine in Tylenol 3.
Codeine in Tylenol 3 is detectable in oral fluid taken in saliva testing for up to four days after ingestion. Codeine use can be detected by a hair follicle test for a longer period—up to three months. If you consume just one poppy seed muffin or two poppy seed bagels, it can trigger a false-positive test result for opiates. Poppy seeds contain trace amounts of codeine. Certain medications, including certain allergy and cold medications diphenhydramine , sleep aids doxylamine , and medications to treat hypertension Verapamil , have been found to cause false-positives for opiates on enzyme immunoassay EIA drug tests as well.
It's important to let the lab clinician know if you have eaten anything or taken any medications or supplements that might affect your results. How long Tylenol 3 is detectable in your body depends on a variety of factors, including the dosage and how often you use the medication as well as your weight, age, metabolism, and overall health. Older adults tend to clear the drug at a slower pace than younger adults.
Your metabolic rate, which can be influenced by age, activity level, and overall health, influences the detection time of Tylenol 3.
In general, the slower your metabolism, the longer the drug will remain in your system. Because the liver and kidneys both play a role in the metabolism of the drug, impaired liver and kidney function can mean that it takes longer to metabolize Tylenol 3.
A higher dose of Tylenol 3 will take longer to process and excrete than a lower dose. Similarly, if you've been taking the drug for some time, it will take longer to clear your system.
Like other drugs, the best way to get Tylenol 3 out of your system is to stop using the drug and give your body time to process and eliminate it. Staying well-hydrated and getting regular exercise can't hurt but this doesn't mean that sweating out or flushing out the drug with tons of water will help. This method will only dilute the drug test and you'll likely have to retake it. If you plan to stop using the drug, work with your doctor.
It's best to taper off of prescriptions containing codeine in order to avoid unpleasant withdrawal symptoms. Codeine also can be extremely dangerous if there's too much of the drug in the body at once, whether it's taken alone or as an active ingredient in Tylenol 3.
Keep from freezing. Acetaminophen and codeine combination oral solution or tablet can cause serious unwanted effects or fatal overdose if taken by children, pets, or adults who are not used to strong narcotic pain medicines. Make sure you store the medicine in a safe and secure place to prevent others from getting it.
Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet.
Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website:www.
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